Recombinant CD41 Monoclonal Antibody

SKU: AN301478L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CD41

Target Synonym:HPA;PPP1R;ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93;GPalpha Iib;Integrin alpha-Iib;Platelet membrane glycoprotein Iib;ITGAB;&alpha-IIb integrin-n;BDPLT16;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;alpha subunit;antigen CD41;antigen CD41);form 2;Integrin;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;integrin αⅡbβ3;ITA2B;platelet fibrinogen receptor;platelet glycoprotein IIb of IIb/IIIa complex;platelet specific antigen BAK

Research Areas:Cardiovascular;Immunology;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A173

UNIProt ID:P08514

Accession:

Background:Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness.

Concentration:1 mg/mL

Immunogen:Recombinant human CD41 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000

Calculated MW:113 kDa

ObservedMW:128 kDa