Recombinant CBP Monoclonal Antibody

SKU: AN301457L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CBP

Target Synonym:CREBBP;CBP;KAT3A;RSTS;RSTS1;CREB binding protein;CREB-binding protein;Cyclic AMP responsive enhancer binding protein;RTS;Rubinstein Taybi syndrome

Research Areas:Epigenetics and Nuclear Signaling;Microbiology;Stem Cells;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A152

UNIProt ID:Q92793

Accession:

Background:CREB-binding protein (CREBBP/CBP), encoded by the human CREBBP gene, is a transcriptional co-activator. CREBBP functions through interactions with transcription factors, mediated by one or more domains: the nuclear receptor interaction domain (RID), the KIX domain (CREB and MYB interaction domain), the cysteine/histidine regions (TAZ1/CH1 and TAZ2/CH3), and the interferon response binding domain. The KIX, TAZ1, and TAZ2 domains of CREBBP bind tightly to the 9aaTADs, the nine amino acid transactivation domains within the tumor suppressor protein p53, thereby influencing its transcriptional activity.

Concentration:1 mg/mL

Immunogen:Synthetic peptide derived from the human CBP protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:3000;IF 1:100-1:200

Calculated MW:300 kDa

ObservedMW:300 kDa