Recombinant Caldesmon/CDM Monoclonal Antibody

SKU: AN301452L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Caldesmon/CDM

Target Synonym:NAG;MGC;CALD1;CDM;H-CAD;HCAD;L-CAD;LCAD;NAG22;caldesmon;CALD 1;Caldesmon 1;Caldesmon 1 Isoform 1;Caldesmon 1 Isoform 2;Caldesmon 1 Isoform 3;Caldesmon 1 Isoform 4;Caldesmon 1 Isoform 5;Caldesmon1;H CAD;L CAD;MGC21352;CAD;CAD;CALD 1;CALD1;CALD1;Caldesmon 1;Caldesmon 1 Isoform 1;Caldesmon 1 Isoform 2;Caldesmon 1 Isoform 3;Caldesmon 1 Isoform 4;Caldesmon 1 Isoform 5;Caldesmon;Caldesmon1;CDM;H CAD;HCAD;L CAD;LCAD;MGC21352;NAG22

Research Areas:Signal Transduction;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A147

UNIProt ID:Q05682

Accession:

Background:Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping.

Concentration:1 mg/mL

Immunogen:Recombinant human Caldesmon/CDM fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000;IF 1:50

Calculated MW:93 kDa

ObservedMW:75 kDa