Recombinant ATF-4 Monoclonal Antibody

SKU: AN301041L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:ATF-4

Target Synonym:ATF;Tax-Responsive Enhancer Element B;TAXREB;ATF4;CREB-2;CREB2;TAXREB67;TXREB;Tax-Responsive Enhancer Element B67;Activating transcription factor 4;ATF 4;ATF4 protein;cAMP-dependent transcription factor ATF-4;cAMP-responsive element-binding protein 2;CREB 2;Cyclic AMP dependent transcription factor ATF 4;Cyclic AMP response element binding protein 2;Cyclic AMP-dependent transcription factor ATF-4;Cyclic AMP-responsive element-binding protein 2;DNA binding protein TAXREB67;DNA-binding protein TAXREB67;Tax Responsive Enhancer Element B67;Tax-responsive enhancer element-binding protein 67;CREB-2

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6C8

UNIProt ID:P18848

Accession:

Background:Activating transcription factor 4(ATF4) Homo sapiens This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human ATF-4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:100-1:200;WB 1:1000-1:5000

Calculated MW:38 kDa

ObservedMW:49 kDa