Recombinant ApoE Monoclonal Antibody

SKU: AN301133L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:ApoE

Target Synonym:MGC;LDLCQ;APOE;AD2;APO-E;ApoE4;LDLCQ5;LPG;apolipoprotein E3;MGC1571;Apolipoprotein E;ApoE

Research Areas:Neuroscience;Cardiovascular;Stem Cells;Signal Transduction;Developmental Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A3

UNIProt ID:P02649

Accession:

Background:The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human ApoE protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:500-1:2000;WB 1:2000-1:10000

Calculated MW:36 kDa

ObservedMW:36 kDa