Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody

SKU: E-AB-81528

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Angiotensin II Type 1 Receptor

Target Synonym:AGTR1;AG2S;AGTR1B;AT1;AT1AR;AT1B;AT1BR;AT1R;AT2R1;HAT1R

Research Areas:Cancer;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R07-1I6

UNIProt ID:P30556

Accession:

Background:Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human Angiotensin II Type 1 Receptor

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000

Calculated MW:41kDa

ObservedMW:41kDa