Rat visfatin,NAMPT ELISA KIT

SKU: E0471Ra

Size:96 Tests-1 Kit

Background:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. {ECO:0000250|UniProtKB:P43490, ECO:0000250|UniProtKB:Q99KQ4}.

Research_area:

Applications:ELISA

Target_protein:Nampt

Reactivity:Rat

Assay type:Sandwich

Sensitivity:2.49ng/L

Detection range:5-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:visfatin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q80Z29

MASS(Da):55438

GeneID:297508

Synonyms:Nampt Pbef1

Gene names:Nampt

Standard solution:2400ng/L