Rat soluble Interleukin-1 receptor type 2,sIL-1R2 ELISA KIT

SKU: E0121Ra

Size:96 Tests-1 Kit

Background:Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:Il1r2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:52.3ng/L

Detection range:100-6400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:soluble interleukin-1 receptor 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43303

MASS(Da):46353

GeneID:117022

Synonyms:Il1r2 Il-1r2 Il1rb

Gene names:Il1r2

Standard solution:12800ng/L