Rat Secreted Frizzled Related Protein 1, SFRP1 ELISA Kit

SKU: E1142Ra

Size:96 Tests-1 Kit

Background:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Research_area:Cell Biology

Applications:ELISA

Target_protein:SFRP1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.023ng/mL

Detection range:0.05-30ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Secreted Frizzled Related Protein 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R168

MASS(Da):18,072

GeneID:84402

Synonyms:Fragment;Secreted frizzled-related protein 1;SFRP1;sFRP-1

Gene names:Sfrp1

Standard solution:32ng/mL