Rat protein phosphatase 1 regulatory subunit 15A,PPP1R15A ELISA KIT

SKU: E2540Ra

Size:96 Tests-1 Kit

Background:Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. {ECO:0000269|PubMed:15674324}.

Research_area:

Applications:ELISA

Target_protein:Ppp1r15a

Reactivity:Rat

Assay type:Sandwich

Sensitivity:7.23ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:protein phosphatase 1 regulatory subunit 15A

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6IN02

MASS(Da):63570

GeneID:171071

Synonyms:Ppp1r15a Gadd34 Myd116 Peg3

Gene names:Ppp1r15a

Standard solution:3200ng/L