Rat Prostaglandin E Synthase, PTGES ELISA Kit

SKU: E1535Ra

Size:96 Tests-1 Kit

Background:Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (PubMed:10869354, PubMed:11067848). Plays a key role in inflammation response, fever and pain (By similarity). Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PTGES

Reactivity:Rat

Assay type:Sandwich

Sensitivity:5.52ng/L

Detection range:10-200ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Prostaglandin E Synthase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JHF3

MASS(Da):17,273

GeneID:59103

Synonyms:Glutathione peroxidase PTGES;Glutathione transferase PTGES;Inducible prostaglandin E Synthase;Microsomal prostaglandin E Synthase 1;mPGES-1;Pges;Prostaglandin E Synthase;PTGES

Gene names:Ptges

Standard solution:2400ng/L