Rat Neurogenic locus notch homolog protein 3,NOTCH3 ELISA KIT

SKU: E1108Ra

Size:96 Tests-1 Kit

Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Acts instructively to control the cell fate determination of CNS multipotent progenitor cells, resulting in astroglial induction and neuron/oligodendrocyte suppression. {ECO:0000250, ECO:0000269|PubMed:11182080}.

Research_area:

Applications:ELISA

Target_protein:Notch3

Reactivity:Rat

Assay type:Sandwich

Sensitivity:52.1pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Neurogenic locus notch homolog protein 3

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R172

MASS(Da):244301

GeneID:56761

Synonyms:Notch3

Gene names:Notch3

Standard solution:12800pg/ml