Rat MCP-3/CCL7 PicoKine® Quick ELISA Kit

SKU: FEK1300

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: CCL7

Specificity: Natural and recombinant rat Ccl7

Background: Chemokine(C-C motif) ligand 7(CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3(MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, mapped the MCP3 gene to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, suggested that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: Q24-P97

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Reference:

Uniprot ID: Q9QXY8

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 287561

Protein Name: C-C motif chemokine 7

Gene Full Name: C-C motif chemokine ligand 7

Synonyms: C C motif chemokine 7; CCL7; chemokine (C C motif) ligand 7; FIC; MARC; MCP 3; MCP3; Monocyte chemotactic protein 3; NC28; SCYA6; SCYA7; Small inducible cytokine A7