Rat HGF/Hepatocyte growth factor ELISA Kit PicoKine®

SKU: EK1301

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: HGF

Specificity: Natural and recombinant rat HGF

Background: Hepatocyte growth factor (HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver injury. HGF has a relative molecular mass (Mr) of 82,000 and is a heterodimer composed of a large alpha-subunit of Mr 69,000 and a small beta-subunit of Mr 34,000.1 The protein consists of 728 amino acid residues, including a possible signal peptide at the N-terminus.2 HGF may serve as a paracrine mediator to control placental development and growth.3 This growth factor may play an important role as a paracrine mediator of the proliferation of melanocytes and endothelial cells, as well as cells of epithelial origin.4 The gene encoding the human HGF is assigned to human chromosome 7.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q33-R495 (alpha) & V496-L728 (beta)

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Reference:

Uniprot ID: P17945

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 24446

Protein Name: Hepatocyte growth factor

Gene Full Name: hepatocyte growth factor

Synonyms: F TCF; Hepatocyte growth factor; Hepatopoeitin A; HGF; HGFB; HPTA; Scatter factor; SF