Rat Heparin-binding EGF-like growth factor,HBEGF ELISA KIT

SKU: E2007Ra

Size:96 Tests-1 Kit

Background:Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:Hbegf

Reactivity:Rat

Assay type:Sandwich

Sensitivity:1.66ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:heparin-binding EGF-like growth factor

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q06175

MASS(Da):22843

GeneID:25433

Synonyms:Hbegf Dtr Hegfl

Gene names:Hbegf

Standard solution:960ng/L