Rat Glutamate Decarboxylase 2, GAD2 ELISA Kit

SKU: E1983Ra

Size:96 Tests-1 Kit

Background:Glutamate decarboxylase 2 is an enzyme that in humans is encoded by the GAD2 gene. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff person syndrome.

Research_area:Others

Applications:ELISA

Target_protein:GAD2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:1.27ng/L

Detection range:2-600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Glutamate decarboxylase 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q05683

MASS(Da):65,402

GeneID:24380

Synonyms:65 kDa glutamic acid decarboxylase;GAD2;gad65;GAD-65;Glutamate decarboxylase 2;Glutamate decarboxylase 65 kDa isoform

Gene names:Gad2

Standard solution:640ng/L