Rat GATA binding protein 4,GATA4 ELISA KIT

SKU: E0061Ra

Size:96 Tests-1 Kit

Background:Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (By similarity). Required during testicular development (By similarity). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (PubMed:15329343). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase (By similarity). {ECO:0000250|UniProtKB:P43694, ECO:0000250|UniProtKB:Q08369, ECO:0000269|PubMed:15329343}.

Research_area:

Applications:ELISA

Target_protein:Gata4

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.21ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:GATA binding protein 4

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P46152

MASS(Da):44597

GeneID:54254

Synonyms:Gata4

Gene names:Gata4

Standard solution:48ng/ml