Rat C-C Motif Chemokine 6, CCL6 ELISA Kit

SKU: E1902Ra

Size:96 Tests-1 Kit

Background:Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced. CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

Research_area:Others

Applications:ELISA

Target_protein:CCL6

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.025ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:C-C motif chemokine 6

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q68FP3

MASS(Da):12,652

GeneID:287910

Synonyms:C-C motif chemokine 6;CCL6;Mrp-1;Scay6;Small-inducible cytokine A6

Gene names:Ccl6

Standard solution:24ng/ml