Rat Apelin Receptor, APLNR ELISA Kit

SKU: E1027Ra

Size:96 Tests-1 Kit

Background:Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed: 11359874). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:APLNR

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.2- 60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Apelin Receptor

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JHG3

MASS(Da):42,349

GeneID:83518

Synonyms:Angiotensin receptor-like 1;Apelin receptor;APLNR;B78;GPCR34;G-protein coupled receptor APJ

Gene names:APLNR

Standard solution:80ng/ml