Rat Apelin, AP ELISA Kit

SKU: E1026Ra

Size:96 Tests-1 Kit

Background:Endogenous ligand for the apelin receptor (APLNR) (PubMed: 11336787, PubMed: 11359874, PubMed: 26611206). Drives internalization of the apelin receptor (PubMed: 11359874). Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR (PubMed: 11336787). Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity). Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (By similarity). Plays a role in early coronary blood vessels formation (By similarity). Mediates myocardial contractility in an ERK1/2-dependent manner (PubMed: 26611206). May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed: 10617103, PubMed: 11359874).

Research_area:Others

Applications:ELISA

Target_protein:APLN

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.524ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Apelin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R0R3

MASS(Da):8,677

GeneID:58812

Synonyms:Apelin;Apelin-13;Apelin-28;Apelin-31;Apelin-36;APJ endogenous ligand;APLN

Gene names:APLN

Standard solution:48ng/mL