Rat 5-Hydroxytryptamine Receptor 2A, HTR2A ELISA Kit

SKU: E1825Ra

Size:96 Tests-1 Kit

Background:G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

Research_area:Neuroscience

Applications:ELISA

Target_protein:HTR2A

Reactivity:Rat

Assay type:Sandwich

Sensitivity:6.89ng/L

Detection range:10-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:5-Hydroxytryptamine Receptor 2A

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P14842

MASS(Da):52,850

GeneID:29595

Synonyms:5-HT-2;5-HT-2A;5-hydroxytryptamine receptor 2A;HTR 2A;HTR2A;Serotonin receptor 2A

Gene names:HTR2A

Standard solution:3200ng/L