RASSF1 Antibody - Cat. #: CSB-PA729792

SKU: CSB-PA729792

Size :50ul

Clone Number:

Aliases:123F2 antibody; Cardiac specific ras association domain family 1 protein antibody; cardiac-specific ras association domain family 1 protein; 123F2 antibody; NORE2A antibody; OTTHUMP00000195503 antibody; OTTHUMP00000195504 antibody; OTTHUMP00000195505 antibody; OTTHUMP00000195507 antibody; Pancreas specific ras association domain family 1 protein antibody; Ras association (RalGDS/AF 6) domain family member 1 antibody; Ras association domain-containing protein 1 antibody; RASF1_HUMAN antibody; Rassf1 antibody; RASSF1A antibody; RDA32 antibody; REH3P21 antibody; Tumor suppressor protein RDA32 antibody; WUGSC:H_LUCA12.5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NS23

Immunogen:Synthetic peptide of Human RASSF1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RASSF1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction