RAD51D Antibody - Cat. #: CSB-PA019268ESR1HU

SKU: CSB-PA019268ESR1HU

Size :50ul

Clone Number:

Aliases:BROVCA4 antibody; DNA repair protein RAD51 homolog 4 antibody; HsTRAD antibody; OTTHUMP00000163851 antibody; OTTHUMP00000163852 antibody; OTTHUMP00000163853 antibody; R51H3 antibody; RA51D_HUMAN antibody; RAD51 homolog D (S. cerevisiae) antibody; RAD51 homolog D antibody; RAD51 like 3 (S. cerevisiae) antibody; RAD51 paralog D antibody; RAD51, S. cerevisiae, homolog of, D antibody; RAD51-like protein 3 antibody; Rad51l3 antibody; Recombination repair protein antibody; S. cerevisiae RAD51-like 3 antibody; TRAD antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75771

Immunogen:Recombinant Human DNA repair protein RAD51 homolog 4 protein (1-328AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAD51D

Research Areas:Epigenetics and Nuclear Signaling