RAD23B Monoclonal Antibody

SKU: BT-MCA2890

Size:100μL

Background:The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:RAD23B

applications:WB, IHC, ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:6D2B3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:RAD23B

Immunogen:Purified recombinant fragment of human RAD23B expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):43.2kDa

UniProt accession:P54727

Synonyms:P58, HR23B, HHR23B

GeneID:5887