RAD18 Antibody - Cat. #: CSB-PA274794

SKU: CSB-PA274794

Size :100ul

Clone Number:

Aliases:2810024C04Rik antibody; DNA repair protein rad18 antibody; E3 ubiquitin-protein ligase RAD18 antibody; EC 6.3.2.- antibody; hHR 18 antibody; hHR18 antibody; hRAD 18 antibody; hRAD18 antibody; MGC156682 antibody; Postreplication repair E3 ubiquitin-protein ligase RAD18 antibody; Postreplication repair protein hRAD18p antibody; Postreplication repair protein RAD18 antibody; RAD 18 antibody; RAD18 antibody; RAD18 homolog (S. cerevisiae) antibody; RAD18 homolog antibody; RAD18 S. cerevisiae homolog antibody; RAD18 S. cerevisiae homolog of antibody; RAD18 transcript variant antibody; RAD18_HUMAN antibody; Rad18sc antibody; Radiation sensitivity protein 18 antibody; RING finger protein 73 antibody; RNF 73 antibody; RNF73 antibody; Structural maintenance of chromosomes protein 6 antibody; YCR066W antibody; YCR66W antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NS91

Immunogen:Synthesized peptide derived from internal of Human RAD18.

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.

Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).
Xin H., Nucleic Acids Res. 28:2847-2854(2000).
Muzny D.M., Nature 440:1194-1198(2006).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAD18

Research Areas:Epigenetics and Nuclear Signaling;Cell biology