RAB35 antibody , Cat. # FNab07019

SKU: FNab07019

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate(PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.

Immunogen:RAB35, member RAS oncogene family

Synonyms:RAB1C, RAY

Observed MW:25 kDa

Uniprot ID:Q15286

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:11021

Research Area:Signal Transduction