Purified Anti-Human CD52 Antibody[5F7]

SKU: AN002860P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD52

Target Synonym:CDW;Epididymal secretory protein E;Human epididymis-specific protein;CAMPATH;CAMPATH-1;CAMPATH-1 antigen;CD52 antigen;CD52 molecule;Epididymal secretory protein E5;HEL-S-171mP;Human epididymis-specific protein 5;CDW52;HE5;CD52; HE5

Research Areas:Immunology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG3, κ

Clonality:Monoclonal

Clone NO.:5F7

UNIProt ID:P31358

Background:CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD52 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:1043