Purified Anti-Human CD22 Antibody[HIB22]

SKU: GBS-F1321A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD22

Target Synonym:Siglec2;B-cell receptor CD22;B-lymphocyte cell adhesion molecule;BL-CAM;CD22;Cd22;Lyb-8;Sialic acid-binding Ig-like lectin 2;Siglec-2;T-cell surface antigen Leu-14

Research Areas:Immunology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:HIB22

UNIProt ID:P20273

Background:CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:

Dilution:

GeneID:933