Purified Anti-Human CD195 Antibody[RoAb13]

SKU: GBS-F14180P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD195

Target Synonym:IDDM;CCCKR;CMKBR;CC-CKR;CKR;CCR;CKR5;CCR-5;CD195;CKR-5;CCCKR5;CMKBR5;IDDM22;CC-CKR-5;CCR5;CCCKR5;CC-CKR-5;CCR-5;CD195;CKR-5;CMKBR5;IDDM22

Research Areas:Neuroscience;Immunology;Microbiology;Signal Transduction;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG2a, κ

Clonality:Monoclonal

Clone NO.:RoAb13

UNIProt ID:P51681

Background:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD195 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:1234