Purified Anti-Human CD163 Antibody[MAC2-158]

SKU: AN004800P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD163

Target Synonym:GHI/;SCARI;CD163;M130;MM130;SCARI1;ED2(rat);GHI/61;Hemoglobin/Haptoglobin Complex Receptor;macrophage-associated antigen;p155;RM3/1; GHI/61

Research Areas:Immunology;Cardiovascular

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:MAC2-158

UNIProt ID:Q86VB7

Background:The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD163 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:9332