PTPRS antibody , Cat. # FNab06948

SKU: FNab06948

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Type II a receptor protein tyrosine phosphatases (rPTP?) are cell surface receptors important for nervous system development, function, and repair.The expression of rPTP? has previously been reported in b-cells and other target organs for INS although the probes chosen did not permit to distinguish between the splice variants.Proteolytic processing near the transmembrane domain generates an extracellular N-terminal E-domain of 130 kDa and a C-terminal P-domain of approximately 85 kDa of rPTP?,and the short splice variants rPTP? 3 and 4 contain an E-domain of 95 kDa (PMID: 16552719). rPTP? expression was observed in tissue lysates of the adult mouse sensory-motor cortex and thoracic spinal cord (T8-T10) as a 75-80kDa immunoreactive band (PMID: 19780196).

Immunogen:protein tyrosine phosphatase, receptor type, S

Synonyms:

Observed MW:75-100 kDa

Uniprot ID:Q13332

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP, FC

Recommended dilution:WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:5802

Research Area:Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience