PSMC2 Polyclonal Antibody

SKU: E-AB-15216

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PSMC2

Target Synonym: 26S protease complex;26S protease regulatory subunit 7;26S proteasome AAA-ATPase subunit RPT1;mammalian suppressor of sgv-1 of yeast;MSS1;Nbla10058;protease 26S subunit 7;proteasome 26S ATPase subunit 2;Proteasome 26S subunit ATPase 2;Proteasome 26S subunit ATPase 2;Protein MSS1;PRS7;PSMC2;putative protein product of Nbla10058;S7

Research Areas: Cancer;Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P35998

Accession:

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human PSMC2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 49kDa

ObservedMW: