PRNP Polyclonal Antibody

SKU: E-AB-18439

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PRNP

Target Synonym: Alternative prion protein; major prion protein;AltPrP;ASCR;CD230;CD230 antigen;CJD;GSS;KURU;Major prion protein;p27 30;PRIO;Prion protein;Prion related protein;PRIP;PRNP;PrP;PrP27 30 ;PrP27-30;PrP33-35C;PrPC;PrPSc;Sinc

Research Areas: Cancer;Neuroscience;Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P04156

Accession:

Background: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human PRNP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:30-1:150

Calculated MW:

ObservedMW: