PR(Phospho Ser294) Polyclonal Antibody

SKU: BT-AP13273

Size:100μL

Background:This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Research_area:Cancer; Epigenetics and nuclear signaling; Neuroscience; Signal transduction

Target_protein:PGR

applications:WB, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Progesterone receptor

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):98981

UniProt accession:Human: P06401; Mouse: Q00175; Rat: Q63449

Synonyms:Progesterone receptor; PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3

GeneID:Human: 5241; Rat: 25154