PPARGC1B antibody , Cat. # FNab06666

SKU: FNab06666

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1(NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Immunogen:peroxisome proliferator-activated receptor gamma, coactivator 1 beta

Synonyms:PERC, PGC1, PGC1B, PPARGC1

Observed MW:100-110 kDa

Uniprot ID:Q86YN6

Reactivity:Human, Mouse

Tested Application:ELISA, IP, WB

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000

Gene ID:133522

Research Area:Metabolism