PODXL Polyclonal Antibody

SKU: D-AB-10420L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PODXL

Target Synonym:GCTM 2 antigen; Gp200; PC; PCLP; PCLP 1; PCLP1; Podocalyxin; podocalyxin like; Podocalyxin like protein 1; PODXL; RCC marker; Renal Cell Carcinoma marker; TRA 1 81;TRA 1 60; TRA-1-60

Research Areas:Cancer;Cardiovascular;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O00592

Accession:

Background:Podocalyxin,also known as podocalyxin-like protein 1 (PODXL or PCLP1),is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus,but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition,podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ～55.5 kDa that undergoes a post‐translational glycosylation,the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns

Concentration:1 mg/mL

Immunogen:Recombinant Human PODXL protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:250-1:500

Calculated MW:55kDa

ObservedMW:160kDa