PLAUR Antibody - Cat. #: CSB-PA628429

SKU: CSB-PA628429

Size :50ul

Clone Number:

Aliases:CD 87 antibody; CD87 antibody; CD87 antigen antibody; MO 3 antibody; MO3 antibody; Monocyte activation antigen Mo3 antibody; Plasminogen activator receptor urokinase antibody; Plasminogen activator urokinase receptor antibody; PLAUR antibody; U PAR antibody; u plasminogen activator receptor antibody; U-PAR antibody; u-plasminogen activator receptor form 2 antibody; UPA receptor antibody; uPAR antibody; UPAR_HUMAN antibody; Urinary plasminogen activator receptor antibody; URKR antibody; Urokinase plasminogen activator receptor antibody; Urokinase plasminogen activator surface receptor antibody; urokinase-type plasminogen activator (uPA) receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q03405

Immunogen:Fusion protein of Human PLAUR

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLAUR

Research Areas:Cancer?Cardiovascular;Immunology