PITX2 Antibody - Cat. #: CSB-PA556975

SKU: CSB-PA556975

Size :50ul

Clone Number:

Aliases:All1 responsive gene 1 antibody; ALL1 responsive protein ARP1 antibody; ALL1-responsive protein ARP1 antibody; ARP 1 antibody; ARP1 antibody; Brx 1 antibody; Brx1 antibody; Homeobox protein PITX2 antibody; IDG 2 antibody; IDG2 antibody; IGDS 2 antibody; IGDS antibody; IGDS2 antibody; IHG 2 antibody; IHG2 antibody; IRID 2 antibody; IRID2 antibody; MGC111022 antibody; MGC20144 antibody; Otlx 2 antibody; Otlx2 antibody; Paired like homeodomain transcription factor 2 antibody; Paired-like homeodomain transcription factor 2 antibody; Pituitary homeo box 2 antibody; Pituitary homeobox 2 antibody; PITX 2 antibody; pitx2 antibody; PITX2_HUMAN antibody; PTX 2 antibody; PTX2 antibody; RGS antibody; RIEG 1 antibody; RIEG antibody; Rieg bicoid related homeobox transcription factor 1 antibody; RIEG bicoid related homeobox transcription factor antibody; RIEG bicoid-related homeobox transcription factor antibody; RIEG1 antibody; RS antibody; Solurshin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99697

Immunogen:Fusion protein of Human PITX2

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PITX2

Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Developmental biology