PIK3R3 Polyclonal Antibody

SKU: E-AB-13018

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PIK3R3

Target Synonym: DKFZp686P05226;FLJ41892;OTTHUMP00000009783;OTTHUMP00000009786;p55;p55 gamma;P55G;p55PIK;Phosphatidylinositol 3 kinase regulatory subunit gamma;Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3;Phosphatidylinositol 3 kinase;regulatory subunit;polypeptide 3 (p55;gamma);Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma;Phosphatidylinositol 3-kinase regulatory subunit gamma;Phosphoinositide 3 kinase regulatory subunit 3 (gamma);Phosphoinositide 3 kinase regulatory subunit 3;Phosphoinositide 3 kinase regulatory subunit polypeptide 3;Phosphoinositide 3 kinase;regulatory subunit 3 (p55;gamma);Phosphoinositide 3 kinase;regulatory subunit;polypeptide 3 (p55;gamma);PI3 kinase p85 subunit gamma;PI3-kinase regulatory subunit gamma;PI3-kinase subunit p55-gamma;PI3K regulatory subunit gamma;Pik3r3;PtdIns 3 kinase p85 gamma;PtdIns-3-kinase regulatory subunit gamma;PtdIns-3-kinase regulatory subunit p55-gamma

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q92569

Accession:

Background: Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human PIK3R3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: