Pig porcine BMP-2 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0311-PO

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Pig

Applications: ELISA

Application Details:

Gene Name: BMP2

Specificity: Natural and recombinant human BMP-2

Background: Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant human BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q283-R396

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Reference:

Uniprot ID: C8C060

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 650

Protein Name: Bone morphogenetic protein 2

Gene Full Name: bone morphogenetic protein 2

Synonyms: BMP-2; BMP 2; BMP 2A; BMP2; BMP2A; bone morphogenetic protein 2; Bone morphogenetic protein 2A