PIF1 Antibody, HRP conjugated - Cat. #: CSB-PA863987LB01HU

SKU: CSB-PA863987LB01HU

Size :50ug

Clone Number:

Aliases:ATP dependent DNA helicase PIF1 antibody; ATP-dependent DNA helicase PIF1 antibody; C15orf20 antibody; DNA helicase homolog PIF1 antibody; DNA helicase PIF1 antibody; DNA repair and recombination helicase PIF1 antibody; Petite integration frequency 1 antibody; PIF antibody; PIF1 5' to 3' DNA helicase antibody; PIF1 5' to 3' DNA helicase homolog antibody; PIF1 antibody; PIF1 DNA helicase antibody; PIF1/RRM3 DNA helicase like protein antibody; PIF1/RRM3 DNA helicase-like protein antibody; PIF1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H611

Immunogen:Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:DNA-dependent ATPase and 5\\\'-3\\\' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PIF1

Research Areas:Epigenetics and Nuclear Signaling