Phospho-PER2 (Ser662) Antibody - Cat. #: CSB-PA217277

SKU: CSB-PA217277

Size :100ul

Clone Number:

Aliases:Circadian clock protein PERIOD 2 antibody; FASPS antibody; FASPS1 antibody; hPER 2 antibody; hPER2 antibody; KIAA0347 antibody; OTTHUMP00000164476 antibody; PER 2 antibody; PER2 antibody; PER2_HUMAN antibody; Period 2 antibody; Period 2 isoform 1 antibody; Period circadian clock 2 antibody; Period circadian protein 2 antibody; Period circadian protein homolog 2 antibody; Period homolog 2 (Drosophila) antibody; Period homolog 2 antibody; Period; Drosophila; homolog of; 2 antibody; Period2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15055

Immunogen:Peptide sequence around phosphorylation site of serine 662 (A-E-S(p)-V-A) derived from Human Period Circadian Protein 2.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100

Background:Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers').

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PER2

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction