Phospho-B-Myb (S577) Polyclonal Antibody

SKU: BT-PHS00540

Size:100μL

Background:The protein encoded by MYBL2, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Cell Biology; Cancer

Target_protein:MYBL2

applications:WB, IF, ELISA

Reactivity:Human, mouse, rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Phospho-B-Myb (S577) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):78764

UniProt accession:Human: P10244; Mouse: P48972

Synonyms:MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2

GeneID:Human: 4605; Mouse: 17865