PGC1 alpha Polyclonal Antibody

SKU: E-AB-65852

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PGC1 alpha

Target Synonym:PPARGC1A;LEM6;PGC-1(alpha);PGC-1alpha;PGC-1v;PGC1;PGC1A;PPARGC1;PPARG coactivator 1 alpha;PGC1 alpha

Research Areas:Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9UBK2

Accession:

Background:The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Concentration:1mg/mL

Immunogen:A synthetic peptide of human PGC1 alpha (NP_037393.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IF 1:50-1:200

Calculated MW:14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa

ObservedMW:110kDa