PFK-2 liv Polyclonal Antibody

SKU: BT-AP07090

Size:100μL

Background:PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for PFKFB1.

Research_area:Signal Transduction; Metabolism

Target_protein:PFKFB1

applications:WB, IHC-p, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PFK-2 liv Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):54681

UniProt accession:Human: P16118; Mouse: P70266; Rat: P07953

Synonyms:PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme

GeneID:Human: 5207; Mouse: 18639; Rat: 24638