PE Anti-Human CD279/PD-1 Antibody[EH12.2H7]

SKU: GBS-F1229D

Size:100Tests

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD279;PD-1

Target Synonym:PD1;PDCD1;Protein PD-1;hPD-1

Research Areas:Cancer Biomarkers;Immunology;Inhibitory Molecules

Conjugation:PE

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:EH12.2H7

UNIProt ID:Q15116

Background:Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

Concentration:5 μL/Test

Control catalog number:E-AB-F09792D

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:5133