PDGFB Antibody - Cat. #: CSB-PA153276

SKU: CSB-PA153276

Size :100ul

Clone Number:

Aliases:Becaplermin antibody; c sis antibody; FLJ12858 antibody; Oncogene SIS antibody; PDGF 2 antibody; PDGF B chain antibody; PDGF Beta antibody; PDGF subunit B antibody; PDGF-2 antibody; PDGF2 antibody; Pdgfb antibody; PDGFB_HUMAN antibody; Platelet derived growth factor 2 antibody; Platelet derived growth factor B chain antibody; Platelet derived growth factor beta antibody; Platelet derived growth factor beta polypeptide (oncogene SIS) antibody; Platelet derived growth factor beta polypeptide (simian sarcoma viral (v sis) oncogene homolog) antibody; Platelet derived growth factor beta polypeptide antibody; Platelet-derived growth factor B chain antibody; Platelet-derived growth factor beta polypeptide antibody; Platelet-derived growth factor subunit B antibody; Proto-oncogene c-Sis antibody; Simian sarcoma viral (v sis) oncogene homolog antibody; SIS antibody; SSV antibody; v sis platelet derived growth factor beta polypeptide antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P01127

Immunogen:Synthesized peptide derived from Human PDGFB.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA By similarity.

Li Fang, Arterioscler. Thromb. Vasc. Biol., Apr 2004; 24: 787 - 792.
EJ Battegay, J. Cell Biol., May 1994; 125: 917.
RA Seifert, J. Biol. Chem., Feb 1993; 268: 4473 - 4480.
Jason Liu, Am J Physiol Lung Cell Mol Physiol, May 1998; 274: 702.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PDGFB

Research Areas:Cancer?Cardiovascular;Developmental biology;Metabolism;Signal transduction