PCGF6 Antibody - Cat. #: CSB-PA871612LA01HU

SKU: CSB-PA871612LA01HU

Size :50ug

Clone Number:

Aliases:MBLR antibody; Mel18 and Bmi1 like RING finger protein antibody; Mel18 and Bmi1-like RING finger antibody; Pcgf6 antibody; PCGF6_HUMAN antibody; Polycomb group RING finger protein 6 antibody; RING finger protein 134 antibody; RNF134 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BYE7

Immunogen:Recombinant Human Polycomb group RING finger protein 6 protein (9-70AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background:Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PCGF6

Research Areas:Epigenetics and Nuclear Signaling