PACSIN2 antibody , Cat. # FNab06101

SKU: FNab06101

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Immunogen:protein kinase C and casein kinase substrate in neurons 2

Synonyms:

Observed MW:60-65 kDa

Uniprot ID:Q9UNF0

Reactivity:Human, Mouse

Tested Application:ELISA, IHC, WB, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:11252

Research Area:Neuroscience, Signal Transduction, Metabolism