ORAI1 antibody , Cat. # FNab06002

SKU: FNab06002

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8C0

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).

Immunogen:ORAI calcium release-activated calcium modulator 1

Synonyms:CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A

Observed MW:32 kDa

Uniprot ID:Q96D31

Reactivity:Human

Tested Application:ELISA, WB,IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500

Gene ID:84876

Research Area:Immunology, Signal Transduction